Niacor

Generic Name: niacin (Oral route)

NYE-a-sin

Commonly used brand name(s)

In the U.S.

• Niacinol


• Niacor


• Niaspan


• Nicotinex


• Slo-Niacin

Available Dosage Forms:

• Tablet


• Tablet, Extended Release


• Capsule


• Capsule, Extended Release


• Elixir

Therapeutic Class: Antihyperlipidemic

Pharmacologic Class: Vitamin B

Chemical Class: Nicotinic Acid (class)

Uses For Niacor

Niacin is used to help lower high cholesterol and fat levels in the blood. This may help prevent medical problems caused by cholesterol and fat clogging the blood vessels.

Some strengths of niacin are available only with your doctor's prescription.

Importance of Diet

Before prescribing medicine for your condition, your doctor will probably try to control your condition by prescribing a personal diet for you. Such a diet may be low in fats, sugars, and/or cholesterol. Many people are able to control their condition by carefully following their doctor's orders for proper diet and exercise. Medicine is prescribed only when additional help is needed and is effective only when a schedule of diet and exercise is properly followed.

Also, Niacor is less effective if you are greatly overweight. It may be very important for you to go on a reducing diet. However, check with your doctor before going on any diet.

Make certain your health care professional knows if you are on any special diet, such as a low-sodium or low-sugar diet.

Before Using This Medicine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

There is no specific information comparing the use of niacin for high cholesterol in children with use in other age groups. However, use is not recommended in children under 2 years of age since cholesterol is needed for normal development.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. Although there is no specific information comparing the use of niacin for high cholesterol in the elderly with use in other age groups, it is not expected to cause different side effects or problems in older people than in younger adults.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Atorvastatin


• Cerivastatin


• Lovastatin


• Pitavastatin


• Rosuvastatin


• Simvastatin

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Warfarin

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

• Ethanol

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Bleeding problems or


• Diabetes mellitus (sugar diabetes) or


• Glaucoma or


• Gout or


• Liver disease or history of jaundice


• Low blood pressure or


• Stomach ulcer—Niacin may make these conditions worse

• Kidney problems—Niacin (extended release tablets) may make your kidney problems worse.

Proper Use of niacin

This section provides information on the proper use of a number of products that contain niacin. It may not be specific to Niacor. Please read with care.

Use this medicine only as directed by your doctor. Do not use more or less of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may increase the chance of unwanted effects.

Remember that niacin will not cure your condition but it does help control it. Therefore, you must continue to take it as directed if you expect to keep your cholesterol levels down.

Follow carefully the special diet your doctor gave you. This is the most important part of controlling your condition, and is necessary if the medicine is to work properly.

If this medicine upsets your stomach, it may be taken with meals or milk. If stomach upset (nausea or diarrhea) continues, check with your doctor.

For patients taking the extended-release capsule form of this medicine:

• Swallow the capsule whole. Do not crush, break, or chew before swallowing. However, if the capsule is too large to swallow, you may mix the contents of the capsule with jam or jelly and swallow without chewing.

For patients taking the extended-release tablet form of this medicine:

• Swallow the tablet whole. If the tablet is scored, it may be broken, but not crushed or chewed, before being swallowed.


• Tablet (Niaspan) should be taken at bedtime after a low-fat snack.


• To decrease flushing of your face (redness), take aspirin or ibuprofen (e.g., Advil, Motrin) 30 minutes before taking tablet (Niaspan).


• Avoid drinking alcohol or hot drinks around the time you take your tablet (Niaspan). This helps decrease flushing of your face (redness).


• Take this medication exactly as your doctor ordered. If you stop taking this medication for any period of time, contact your doctor prior to restarting taking niacin.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (extended-release capsules, extended-release tablets, oral solution, or regular tablets):
  
  • For treatment of high cholesterol:
    
    • Adults and teenagers—500 milligrams to 2 grams one to three times a day: use and dose will be determined by your doctor. Do not exceed the amount the doctor prescribes.
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Niacor

It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly to lower your cholesterol and triglyceride (fat) levels and if you should continue to take it.

Do not stop taking niacin without first checking with your doctor. When you stop taking this medicine, your blood cholesterol levels may increase again. Your doctor may want you to follow a special diet to help prevent this from happening.

Do not take vitamins or other dietary supplements unless they have been discussed with your doctor. This especially includes vitamins or dietary supplements that contain niacin or similar ingredients.

This medicine may affect blood sugar levels. If you notice a change in the results of your blood or urine sugar tests or if you have any questions, check with your doctor.

This medicine may cause you to feel dizzy or faint, especially when you get up from a lying or sitting position. Getting up slowly may help. This effect should lessen after a week or two as your body gets used to the medicine. However, if the problem continues or gets worse, check with your doctor.

Niacor Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less commonWith prolonged use of extended-release niacin

• Darkening of urine


• light gray-colored stools


• loss of appetite


• severe stomach pain


• yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

• Abdominal pain


• feeling of warmth


• flushing or redness of skin, especially on face and neck


• headache


• rash


• runny nose


• sneezing


• stuffy nose

With high doses

• Diarrhea


• dizziness or faintness


• dryness of skin


• fever


• frequent urination


• itching of skin


• joint pain


• muscle aching or cramping


• nausea or vomiting


• side, lower back, or stomach pain


• swelling of feet or lower legs


• unusual thirst


• unusual tiredness or weakness


• unusually fast, slow, or irregular heartbeat

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Niacor side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Niacor resources

• Niacor Side Effects (in more detail)
• Niacor Use in Pregnancy & Breastfeeding
• Drug Images
• Niacor Drug Interactions
• Niacor Support Group
• 0 Reviews for Niacor - Add your own review/rating

• Niacor MedFacts Consumer Leaflet (Wolters Kluwer)


• Niacor Prescribing Information (FDA)


• Niacor nicotinic acid Concise Consumer Information (Cerner Multum)


• Niacin Monograph (AHFS DI)


• Slo-Niacin Controlled-Release Capsules MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Niacor with other medications

• High Cholesterol
• Hyperlipoproteinemia
• Hyperlipoproteinemia Type IV, Elevated VLDL
• Hyperlipoproteinemia Type V, Elevated Chylomicrons VLDL
• Niacin Deficiency
• Pellagra

IbuTAD

IbuTAD may be available in the countries listed below.

Ingredient matches for IbuTAD

Ibuprofen

Ibuprofen is reported as an ingredient of IbuTAD in the following countries:

• Germany

International Drug Name Search

Novo-Cisapride

Generic Name: cisapride (Oral route)

SIS-a-pride

Commonly used brand name(s):

In Canada

• Novo-Cisapride


• Prepulsid

Available Dosage Forms:

• Suspension


• Tablet

Therapeutic Class: Stimulant, Gastrointestinal

Uses For Novo-Cisapride

Cisapride is a medicine that increases the movements or contractions of the stomach and intestines. It is used to treat symptoms such as heartburn caused by a backward flow of stomach acid into the esophagus.

Cisapride will only be available in the U.S. to certain patients who meet eligibility criteria from the manufacturer. Your doctor must enroll in a special program in order to prescribe this medicine for you. Cisapride is not available in Canada.

This medicine was available only with your doctor's prescription.

Janssen Pharmaceutica stopped marketing Propulsid® (cisapride) and has made it available only through an investigational limited access program .

Before Using Novo-Cisapride

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Cisapride can cause serious side effects in any patient. Therefore, it is especially important that you discuss with the child's doctor the good that this medicine may do, as well as the risks of using it.

Geriatric

Elderly people are especially sensitive to the effects of cisapride. Cisapride stays in the body longer so the dose may be different than in younger people.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Acecainide


• Acetophenazine


• Ajmaline


• Amiodarone


• Amisulpride


• Amitriptyline


• Amoxapine


• Amprenavir


• Aprepitant


• Aprindine


• Arsenic Trioxide


• Astemizole


• Atazanavir


• Azimilide


• Bepridil


• Bretylium


• Chloral Hydrate


• Chloroquine


• Chlorpromazine


• Clarithromycin


• Clomipramine


• Dalfopristin


• Darunavir


• Delavirdine


• Desipramine


• Diltiazem


• Disopyramide


• Dofetilide


• Dolasetron


• Dothiepin


• Doxepin


• Dronedarone


• Droperidol


• Efavirenz


• Enflurane


• Erythromycin


• Ethopropazine


• Flecainide


• Fluconazole


• Fluphenazine


• Fluvoxamine


• Fosamprenavir


• Fosaprepitant


• Foscarnet


• Gatifloxacin


• Gemifloxacin


• Grepafloxacin


• Halofantrine


• Haloperidol


• Halothane


• Ibutilide


• Imipramine


• Indinavir


• Isoflurane


• Isradipine


• Itraconazole


• Ketoconazole


• Levomethadyl


• Lidoflazine


• Lofepramine


• Lorcainide


• Maprotiline


• Mefloquine


• Mesoridazine


• Methadone


• Methotrimeprazine


• Mibefradil


• Moricizine


• Moxifloxacin


• Nefazodone


• Nelfinavir


• Nortriptyline


• Octreotide


• Opipramol


• Pentamidine


• Perphenazine


• Pimozide


• Pipotiazine


• Pirmenol


• Posaconazole


• Prajmaline


• Probucol


• Procainamide


• Prochlorperazine


• Promazine


• Promethazine


• Propafenone


• Propiomazine


• Protriptyline


• Quetiapine


• Quinidine


• Quinupristin


• Ranolazine


• Recainam


• Risperidone


• Ritonavir


• Saquinavir


• Sematilide


• Sertindole


• Sotalol


• Sparfloxacin


• Spiramycin


• Sulfamethoxazole


• Sultopride


• Tedisamil


• Telithromycin


• Terfenadine


• Terodiline


• Thiethylperazine


• Thioridazine


• Tipranavir


• Trifluoperazine


• Triflupromazine


• Trimeprazine


• Trimethoprim


• Trimipramine


• Troleandomycin


• Vasopressin


• Voriconazole


• Ziprasidone


• Zolmitriptan


• Zotepine

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Iloperidone


• Lapatinib


• Lumefantrine


• Nilotinib


• Sunitinib


• Tetrabenazine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Acenocoumarol


• Anisindione


• Betel Nut


• Cyclosporine


• Dicumarol


• Nevirapine


• Phenindione


• Phenprocoumon


• Warfarin

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Using this medicine with any of the following is not recommended. Your doctor may decide not to treat you with this medication, change some of the other medicines you take, or give you special instructions about the use of food, alcohol, or tobacco.

• Grapefruit Juice

Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

• Ethanol

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Abdominal or stomach bleeding or


• Intestinal blockage—Cisapride may make these conditions worse.

• Heart disease or


• Kidney disease, severe, or


• Low potassium blood levels or


• Lung disease, severe—Cisapride may cause an increased risk of serious heart rhythm problems.

Proper Use of cisapride

This section provides information on the proper use of a number of products that contain cisapride. It may not be specific to Novo-Cisapride. Please read with care.

Take this medicine 15 minutes before meals and at bedtime with a beverage, unless otherwise directed by your doctor.

Grapefruit and grapefruit juice may increase the effects of cisapride by increasing the amount of this medicine in the body. You should not eat grapefruit or drink grapefruit juice while you are taking this medicine.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage forms (tablets and suspension):
  
  • For heartburn caused by gastroesophageal reflux:
    
    • Adults and children 12 years of age and older—5 to 20 milligrams (mg) of cisapride two to four times a day. Cisapride should be taken fifteen minutes before meals and at bedtime.
    
    
    • Children up to 12 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 0.15 to 0.3 mg of cisapride per kilogram (0.07 to 0.14 mg per pound) of body weight three to four times a day, fifteen minutes before meals.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Novo-Cisapride

This medicine may cause your body to absorb alcohol more quickly than you normally would. Therefore, you may notice the effects sooner. Check with your doctor before drinking alcohol while you are using this medicine.

This medicine may cause some people to become dizzy, drowsy, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert.

Novo-Cisapride Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

• Blurred vision or other changes in vision


• convulsions (seizures)


• dizziness


• fainting or feeling faint


• fast or racing heartbeat


• pounding or irregular heartbeat


• swelling of face, hands, lower legs, and/or feet


• unusual weight gain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common or rare

• Abdominal pain or cramping


• constipation


• diarrhea


• drowsiness


• dryness of mouth


• gas


• headache


• heartburn or indigestion


• nausea


• runny nose


• tremor


• unusual tiredness or weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Healthcare does not assume any responsibility or risk for your use of the Thomson Healthcare products.

More Novo-Cisapride resources

• Novo-Cisapride Side Effects (in more detail)
• Novo-Cisapride Use in Pregnancy & Breastfeeding
• Novo-Cisapride Drug Interactions
• Novo-Cisapride Support Group
• 1 Review for Novo-Cisapride - Add your own review/rating

Compare Novo-Cisapride with other medications

• Gastroparesis
• GERD
• Indigestion

Premique

Premique may be available in the countries listed below.

UK matches:

• Premique 0.625mg/5mg Coated Tablets
• Premique Cycle 0.625mg/10mg Coated Tablets
• Premique Low Dose 0.3mg/1.5mg Modified Release Tablets
• Premique 0.625mg/5mg Coated Tablets. (SPC)
• Premique Cycle 0.625mg/10mg Coated Tablets (SPC)
• Premique Low Dose 0.3mg/1.5mg Modified Release Tablets (SPC)

Ingredient matches for Premique

Conjugated Estrogens

Estrogens, conjugated is reported as an ingredient of Premique in the following countries:

• Malta


• United Kingdom

Medroxyprogesterone

Medroxyprogesterone 17α-acetate (a derivative of Medroxyprogesterone) is reported as an ingredient of Premique in the following countries:

• Malta


• United Kingdom

International Drug Name Search

Glossary

SPC	Summary of Product Characteristics (UK)

Click for further information on drug naming conventions and International Nonproprietary Names.

Erit

Erit may be available in the countries listed below.

Ingredient matches for Erit

Erythromycin

Erythromycin ethylsuccinate (a derivative of Erythromycin) is reported as an ingredient of Erit in the following countries:

• Argentina

International Drug Name Search

Lonox

Pronunciation: AT-row-peen/dye-fen-OX-i-late
Generic Name: Atropine/Diphenoxylate
Brand Name: Examples include Lomotil and Lonox

Lonox is used for:

Treating diarrhea. It may also be used for other conditions as determined by your doctor.

Lonox is an antidiarrheal and anticholinergic combination. It works by decreasing the motion of muscles in the intestines and prolonging the time it takes to move the contents through the body.

Do NOT use Lonox if:

• you are allergic to any ingredient in Lonox


• you have diarrhea caused by certain conditions (eg, pseudomembranous colitis, enterotoxin-producing bacteria, food poisoning)


• you have jaundice (yellowing of the eyes or skin)


• you have a blockage of the stomach or bowel, angle-closure glaucoma, myasthenia gravis, urinary blockage, excess acid in the stomach or throat, esophagus problems (eg, difficulty swallowing, inflammation), bowel muscle weakness, or heart problems with severe bleeding


• you are taking sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Lonox:

Some medical conditions may interact with Lonox. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a history of jaundice (yellowing of the eyes or skin) or megacolon


• if you have abnormal blood levels of electrolytes (eg, potassium, sodium), ulcerative colitis, liver or kidney problems, Down syndrome, numbness due to nerve damage, prostate problems (enlarged prostate), a blockage of the bladder, trouble urinating, heart problems (eg, congestive heart failure, irregular heartbeat), hiatal hernia, asthma, open-angle glaucoma, or risk factors for glaucoma


• if you are dehydrated

Some MEDICINES MAY INTERACT with Lonox. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Antihistamines (eg, diphenhydramine), medicine for Parkinson disease (eg, benztropine), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Lonox's side effects


• Barbiturates (eg, phenobarbital) or sodium oxybate (GHB) because the risk of their side effects may be increased by Lonox


• Monoamine oxidase inhibitors (MAOIs) (eg, phenelzine) because the risk of serious side effects, including severe high blood pressure, may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Lonox may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Lonox:

Use Lonox as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Lonox by mouth with or without food.


• If you miss a dose of Lonox and you are taking it regularly, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Lonox.

Important safety information:

• Lonox may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Lonox with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Lonox; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.


• Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor. This could increase the risk of serious side effects.


• If your symptoms do not get better within 10 days (2 days for children) or if they get worse, check with your doctor.


• Do not become overheated in hot weather or while you are being active; heatstroke may occur.


• Report any symptoms of fluid or electrolyte loss to your doctor: dry mouth; thirst; weakness; lethargy; drowsiness; restlessness; muscle pain or cramps; muscle weakness; low blood pressure; infrequent urination; rapid heartbeat; stomach disorders such as nausea and vomiting.


• Lonox may make your eyes more sensitive to sunlight. It may help to wear sunglasses.


• Tell your doctor or dentist that you take Lonox before you receive any medical or dental care, emergency care, or surgery.


• Use Lonox with caution in the ELDERLY; they may be more sensitive to its effects, especially excitement, agitation, or drowsiness.


• Lonox should not be used in CHILDREN younger than 13 years old; safety and effectiveness in these children have not been confirmed.


• Caution is advised when using Lonox in CHILDREN 13 years of age and older; they may be more sensitive to its effects.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Lonox while you are pregnant. Lonox is found in breast milk. If you are or will be breast-feeding while you use Lonox, check with your doctor. Discuss any possible risks to your baby.

When used for longer than a few weeks or at high doses, some people develop a need to continue taking Lonox. This is known as DEPENDENCE or addiction. Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.

Possible side effects of Lonox:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; constipation; decreased sweating; difficulty sleeping; dizziness; drowsiness; dry mouth, nose, or skin; headache; loss of appetite; loss of taste; nausea; nervousness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); abdominal bloating or swelling; agitation; changes in heartbeat; confusion; continued or severe diarrhea; delirium; difficulty focusing your eyes; difficulty urinating; exaggerated sense of well-being; excitement; fast/irregular heartbeat; fever; hallucinations; numbness of the hands or feet; severely enlarged pupils; severe or prolonged restlessness; speech disturbance; unusual weakness; vomiting.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Lonox side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include coma; difficulty breathing; dilated or constricted pupils; disorientation; fever; flushing; hallucinations; hyperactivity; muscle weakness; restlessness; seizures; severe dizziness; unusual eye movements; urinary retention; vomiting.

Proper storage of Lonox:

Store Lonox at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Lonox out of the reach of children and away from pets.

General information:

• If you have any questions about Lonox, please talk with your doctor, pharmacist, or other health care provider.


• Lonox is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Lonox. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Lonox resources

• Lonox Side Effects (in more detail)
• Lonox Use in Pregnancy & Breastfeeding
• Drug Images
• Lonox Drug Interactions
• Lonox Support Group
• 1 Review for Lonox - Add your own review/rating

• Lonox Advanced Consumer (Micromedex) - Includes Dosage Information


• Lonox Concise Consumer Information (Cerner Multum)


• Lomotil Prescribing Information (FDA)

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Lescol XL Extended-Release Tablets

Pronunciation: FLOO-va-STAT-in
Generic Name: Fluvastatin
Brand Name: Lescol XL

Lescol XL Extended-Release Tablets are used for:

Lowering high cholesterol and triglycerides in certain patients. It also increases high-density lipoprotein (HDL, "good") cholesterol levels. It is used along with an appropriate diet. It is used in certain patients to slow blood vessel blockage and to reduce the need for medical procedures to open blocked heart blood vessels. It may also be used for other conditions as determined by your doctor.

Lescol XL Extended-Release Tablets are an HMG-CoA reductase inhibitor, also known as a "statin." It works by reducing the production of certain fatty substances in the body, including cholesterol.

Do NOT use Lescol XL Extended-Release Tablets if:

• you are allergic to any ingredient in Lescol XL Extended-Release Tablets


• you have liver problems or unexplained abnormal liver function tests


• you are pregnant or breast-feeding

Contact your doctor or health care provider right away if any of these apply to you.

Before using Lescol XL Extended-Release Tablets:

Some medical conditions may interact with Lescol XL Extended-Release Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have low blood pressure, a serious infection, kidney problems, diabetes, or a history of seizures


• if you have metabolism, hormonal, or electrolyte problems


• if you drink alcohol or have a history of liver problems or alcohol abuse


• if you have recently had major surgery or a serious injury


• if you have a certain type of high cholesterol (homozygous familial hypercholesterolemia)

Some MEDICINES MAY INTERACT with Lescol XL Extended-Release Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Azole antifungals (eg, fluconazole), colchicine, erythromycin, fibrates (eg, clofibrate, gemfibrozil), H₂ blockers (eg, ranitidine), immunosuppressants (eg, cyclosporine), niacin, or omeprazole because they may increase the risk of muscle or kidney problems


• Anticoagulants (eg, warfarin) because the risk of bleeding may be increased


• Rifampin because it may decrease Lescol XL Extended-Release Tablets's effectiveness


• Cimetidine, digoxin, glyburide, ketoconazole, phenytoin, or spironolactone because the risk of their side effects may be increased by Lescol XL Extended-Release Tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if Lescol XL Extended-Release Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Lescol XL Extended-Release Tablets:

Use Lescol XL Extended-Release Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Lescol XL Extended-Release Tablets by mouth with or without food.


• Swallow Lescol XL Extended-Release Tablets whole. Do not break, crush, or chew before swallowing.


• If you take cholestyramine or colestipol, ask your doctor or pharmacist how to take it with Lescol XL Extended-Release Tablets.


• Continue to take Lescol XL Extended-Release Tablets even if you feel well. Do not miss any doses.


• If you miss a dose of Lescol XL Extended-Release Tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Lescol XL Extended-Release Tablets.

Important safety information:

• Lescol XL Extended-Release Tablets may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Lescol XL Extended-Release Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Drinking alcohol daily or in large amounts may increase the risk of liver problems with Lescol XL Extended-Release Tablets. Check with your doctor before drinking alcohol while you are taking Lescol XL Extended-Release Tablets.


• Follow the diet and exercise program given to you by your health care provider.


• Tell your doctor or dentist that you take Lescol XL Extended-Release Tablets before you receive any medical or dental care, emergency care, or surgery.


• Women who may become pregnant should use effective birth control while taking Lescol XL Extended-Release Tablets. Check with your doctor if you have questions about using birth control.


• Do NOT take more than the recommended dose without checking with your doctor.


• Report any unexplained muscle pain, tenderness, or weakness to your doctor right away, especially if you also have a fever or general body discomfort.


• Lab tests, including blood cholesterol levels and liver function tests, may be performed while you use Lescol XL Extended-Release Tablets. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Lescol XL Extended-Release Tablets should be used with extreme caution in CHILDREN younger than 9 years old and in those who have been having a menstrual period for less than one year; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: Do not use Lescol XL Extended-Release Tablets if you are pregnant. It may cause harm to the fetus. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. Lescol XL Extended-Release Tablets are found in breast milk. Do not breast-feed while you are taking Lescol XL Extended-Release Tablets.

Possible side effects of Lescol XL Extended-Release Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Headache; stomach pain or upset.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); change in the amount of urine produced; chest pain; dark urine; decreased sexual desire or ability; fever, chills, or persistent sore throat; flu-like symptoms; joint pain; mental or mood changes; muscle pain, tenderness, or weakness (with or without fever or fatigue); numbness or tingling of the skin, arm, or leg; painful or frequent urination; pale stools; red, swollen, blistered, or peeling skin; severe stomach pain; yellowing of the eyes or skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Lescol XL side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Lescol XL Extended-Release Tablets:

Store Lescol XL Extended-Release Tablets at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Keep Lescol XL Extended-Release Tablets out of the reach of children and away from pets.

General information:

• If you have any questions about Lescol XL Extended-Release Tablets, please talk with your doctor, pharmacist, or other health care provider.


• Lescol XL Extended-Release Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Lescol XL Extended-Release Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Lescol XL resources

• Lescol XL Side Effects (in more detail)
• Lescol XL Use in Pregnancy & Breastfeeding
• Drug Images
• Lescol XL Drug Interactions
• Lescol XL Support Group
• 0 Reviews for Lescol XL - Add your own review/rating

Compare Lescol XL with other medications

• High Cholesterol
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• Hyperlipoproteinemia
• Hyperlipoproteinemia Type IIa, Elevated LDL
• Hyperlipoproteinemia Type IIb, Elevated LDL VLDL